Our SHARP (Small-Scale Highly Accurate and Reproducible Platform) Cell  Metabolome Assay: SHARP-CMA is a cutting-edge solution for high-sensitivity metabolome profiling designed specifically for researchers working with small quantities of cells. This innovative service enables the precise identification and accurate relative quantification of metabolites from as few as 5,000 cells per sample.

Amino Acids: Amino acids are organic compounds that serve as the building blocks of proteins. They form enzymes, hormones, and neurotransmitters, and contribute to metabolism, energy production, and biomolecule synthesis like nucleotides.

  • Examples: Alanine, Cysteine, Arginine, Asparagine, Glutamine, Glycine, and Relevant Metabolism

Pyrimidine & Purine Metabolism: Pyrimidines and purines are nitrogenous bases forming the building blocks of nucleotides, vital components of DNA and RNA. Their metabolism is crucial for genetic information storage, energy transfer, and cellular signalling processes.

  • Examples: Thymine, Cytosine, Uracil, Adenine, Guanine, and AMP/Guanine/ATP

Energy-Related Metabolites: are small molecules involved in the biochemical pathways that produce, store, and utilize energy within cells, such as glucose and NADH. They play a crucial role in maintaining cellular functions by driving processes like metabolism, signalling, and repair.

  • Examples: Glucose, Oxaloacetetic Acid, Pyruvic Acid, Alpha-Ketoglutaric Acid, Succinic Acid, and Fumaric Acid
  • Basic SHARP-CMA: Up to 700 metabolites and 1,050 metabolite candidates [see list].
  • Elevated SHARP-CMA: Up to 950 metabolites and 2,000 metabolite candidates [see list].
  • Comprehensive SHARP-CMA: Up to 1,200 metabolites and 3,900 metabolite candidates [see list].

Note: The number of metabolites that can be identified or detected may vary depending on the specific cell type.

Basic SHARP-CMA

  • Academic/Government: $169 CAD per sample
  • Industry: $219.70 CAD per sample

Elevated SHARP-CMA 

  • Academic/Government: $299 CAD per sample
  • Industry: $388.70 CAD per sample

Comprehensive SHARP-CMA

  • Academic/Government: $559 CAD per sample
  • Industry: $726.70 CAD per sample

Flexible SHARP-CMA 

  • Please inquire
  • The above prices apply to a sample size of 20 or more. For less than 20 samples, an additional $400 CAD applies per channel.
  • All services require a flat fee of $200 CAD for sample handling per project.

Our SHARP Metabolomics Platform requires a specific sample amount depending on the selected service mode:

  • Basic SHARP-CMA: minimum cell count is 5,000 cells; preferred cell count is 20,000 cells 
  • Elevated SHARP-CMA: minimum cell count is 10,000 cells; preferred cell count is 40,000 cells 
  • Comprehensive SHARP-CMA: minimum cell count is 20,000 cells; preferred cell count is 80,000 cells
  • Flexible SHARP-CMA: minimum cell count is 20,000 cells per channel 

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